SYRE - Spyre Therapeutics, Inc. Stock Analysis & Valuation

Spyre Therapeutics, Inc. (SYRE) trades at $96.56 with an EquitAI Valuation DNA score of 8/10 and Quality score of 3/10. These scores evaluate balance sheet leverage, free cash flow generation, and fundamental multiples against historical benchmarks.

Wall Street analysts have a consensus 12-month price target of $119.9 for Spyre Therapeutics, Inc. (SYRE), representing an implied 24.2% upside from its current trading level of $96.56 with an average rating of Buy based on 9 analyst ratings. Individual analyst price targets range from a low of $107.0 to a high of $130.0, with a median forecast of $120.0. EquitAI benchmarks analyst consensus projections against intrinsic Financial DNA valuation pillars.

Spyre Therapeutics, Inc. does not currently pay a regular dividend yield, prioritizing capital reinvestment into operations, product development, and balance sheet strength.

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